AN NMR-STUDY OF CHIRAL RECOGNITION RELEVANT TO THE LIQUID-CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS BY A CELLULOSE DERIVATIVE

被引：49

作者：

YASHIMA, E ^{[1
]}

YAMADA, M ^{[1
]}

OKAMOTO, Y ^{[1
]}

机构：

[1] NAGOYA UNIV, FAC ENGN, DEPT APPL CHEM, CHIKUSA KU, NAGOYA 46401, JAPAN

来源：

CHEMISTRY LETTERS | 1994年 / 03期

关键词：

D O I：

10.1246/cl.1994.579

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral discrimination of enantiomers by cellulose tris(4-trimethylsilylphenylcarbamate) (CTSP) was studied by H-1 NMR spectroscopy. The H-1 NMR signals of trans-stilbene oxide and 2-butanol were enantiomerically separated into two sets of peaks in the presence of CTSP in CDCl3. The competition experiment with acetone suggests that trans-stilbene oxide may be adsorbed on the NH proton of carbamate residues of CTSP. Chemical shift non-equivalence in enantiotopic methyl groups of 2-propanol was observed in the presence of CTSP.

引用

页码：579 / 582

页数：4

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