SYNTHESIS OF A BIANTENNARY HEPTASACCHARIDE BY REGIOSELECTIVE GLYCOSYLATIONS

被引：62

作者：

UNVERZAGT, C

机构：

[1] Institut Für Organische Chemie Und Biochemie, Technischen Universität München, Garching, D-85748

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 10期

关键词：

D O I：

10.1002/anie.199411021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A single protective group is sufficient at β‐mannoside for the selective introduction of both side chains of A. The key glycosylations at the branching point proceed with high regioselectivity when 4,6‐O‐benzylidene acetal is used as a temporary protecting group. Protected heptasaccharide A was synthesized as a precursor of the undecasaccharide‐asparagine found on glycoproteins and shown below. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1102 / 1104

页数：3

共 26 条

[1] THE USE OF IMMOBILIZED GLYCOSYLTRANSFERASES IN THE SYNTHESIS OF SIALYLOLIGOSACCHARIDES [J].