DEVELOPMENT AND EVALUATION OF 2 AUTOMATED METHODS FOR QUANTIFYING HUMAN MUSCLE SYMPATHETIC-NERVE ACTIVITY

被引：9

作者：

ROTHMAN, JLS

EASTY, AC

FRECKER, RC

FLORAS, JS

机构：

[1] TORONTO GEN HOSP,DIV CARDIOL,200 ELIZABETH ST,TORONTO M5G 2C4,ONTARIO,CANADA

[2] TORONTO GEN HOSP,DEPT MED ENGN,TORONTO M5G 2C4,ONTARIO,CANADA

[3] UNIV TORONTO,INST BIOMED ENGN,TORONTO M5S 1A4,ONTARIO,CANADA

来源：

COMPUTERS IN BIOLOGY AND MEDICINE | 1991年 / 21卷 / 04期

基金：

英国医学研究理事会; 加拿大自然科学与工程研究理事会;

关键词：

AUTONOMIC NERVOUS SYSTEM; BARORECEPTOR REFLEX; DIGITAL SIGNAL PROCESSING; HUMANS; MICRONEUROGRAPHY; SYMPATHETIC NERVE ACTIVITY;

D O I：

10.1016/0010-4825(91)90004-S

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The microneurographic technique of directly recording muscle sympathetic nerve activity (SNA) in conscious humans was developed over 20 yr ago, but analysis and quantification of the resultant mean voltage neurogram has been largely by visual inspection by a trained observer. Two computer-assisted methods were developed to quantitate these bursts of efferent activity: peak detection, and ECG R-wave-triggered burst averaging. Peak detection was optimized using statistical techniques; burst averaging was compared to both the manual technique and to the peak detection method. Burst averaging was found to be the superior method because of its speed, consistency, and objectivity.

引用

页码：221 / 235

页数：15