DOES A SYNTHETIC PEPTIDE-CONTAINING THE LEUCINE-ZIPPER DOMAIN OF C-MYB FORM AN ALPHA-HELICAL STRUCTURE IN SOLUTION

被引：7

作者：

EBNETH, A

ADERMANN, K

WOLFES, H

机构：

[1] HANNOVER MED SCH,ZENTRUM BIOCHEM,INST BIOPHYS CHEM,D-30625 HANNOVER,GERMANY

[2] INST PEPTIDFORSCH,D-30625 HANNOVER,GERMANY

来源：

FEBS LETTERS | 1994年 / 337卷 / 03期

关键词：

C-MYB; PROTOONCOGENE; LEUCINE ZIPPER; CIRCULAR DICHROISM SPECTROSCOPY;

D O I：

10.1016/0014-5793(94)80205-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have examined a synthetic peptide containing the putative leucine zipper domain of the chicken c-myb proto-oncogene using circular dichroism (CD) spectroscopy. The peptide adopts an alpha-helical structure only at low temperatures and in the presence 2,2,2-trifluoroethanol.

引用

页码：265 / 268

页数：4

共 18 条

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