Reduced level of 25-hydroxyvitamin D in chronic/relapsing Alopecia Areata

被引:45
作者
d'Ovidio, Roberto [1 ]
Vessio, Margherita [2 ]
d'Ovidio, Francesco Domenico [3 ]
机构
[1] Trichol Grp Associaz Italiana Dermatologi Am, Bari, Italy
[2] Osped Generale Regionale, Div Dermatol, Bari, Italy
[3] Univ Bari, Dept Econ & Math, Bari, Italy
关键词
Alopecia Areata; vitamin D; autoimmunity; seasonality;
D O I
10.4161/derm.24411
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
Current observations link vitamin D deficiency to many autoimmune diseases. There are limited data on vitamin D in Alopecia Areata, an autoimmune disease which in our experience shows seasonality in most of its remitting-relapsing forms. Our results demonstrate the presence of insufficiency of 25-hydroxyvitamin D (25OH -D) in many patients with various clinical forms, correlated with the expected increase of the values of Parathyroid Hormone (PTH). This could suggest the possible clinical use of vitamin D in the management of this frustrating disease.
引用
收藏
页码:271 / 273
页数:3
相关论文
共 11 条
[1]
Can supplementation with vitamin D reduce the risk or modify the course of autoimmune diseases? A systematic review of the literature [J].
Antico, Antonio ;
Tampoia, Marilina ;
Tozzoli, Renato ;
Bizzaro, Nicola .
AUTOIMMUNITY REVIEWS, 2012, 12 (02) :127-136
[2]
Vitamin D and autoimmunity: New aetiological and therapeutic considerations [J].
Arnson, Yoav ;
Amital, Howard ;
Shoenfeld, Yehuda .
ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 (09) :1137-1142
[3]
Longitudinal evaluation of vitamin D status in healthy subjects from Southern Italy: Seasonal and gender differences [J].
Carnevale, V ;
Modoni, S ;
Pileri, M ;
Di Giorgio, A ;
Chiodini, I ;
Minisola, S ;
Vieth, R ;
Scillitani, A .
OSTEOPOROSIS INTERNATIONAL, 2001, 12 (12) :1026-1030
[4]
d'Ovidio R., 2009, G ITAL TRICOL 2009, V24, P5
[5]
D'Ovidio R, 1995, GIORN ITAL DERMAT V, V295, P130
[6]
d'Ovidio Roberto, 2011, Int J Trichology, V3, P43, DOI 10.4103/0974-7753.82130
[7]
Successful Treatment of Alopecia Areata with Topical Calcipotriol [J].
Kim, Dong Ha ;
Lee, Jin Woong ;
Kim, In Su ;
Choi, Sun Young ;
Lim, Yun Young ;
Kim, Hyeong Mi ;
Kim, Beom Joon ;
Kim, Myeung Nam .
ANNALS OF DERMATOLOGY, 2012, 24 (03) :341-344
[8]
Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T cells by 1,25-dihydroxyvitamin D3 [J].
Penna, G ;
Roncari, A ;
Amuchastegui, S ;
Daniel, KC ;
Berti, E ;
Colonna, M ;
Adorini, L .
BLOOD, 2005, 106 (10) :3490-3497
[9]
The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know [J].
Ross, A. Catharine ;
Manson, JoAnn E. ;
Abrams, Steven A. ;
Aloia, John F. ;
Brannon, Patsy M. ;
Clinton, Steven K. ;
Durazo-Arvizu, Ramon A. ;
Gallagher, J. Christopher ;
Gallo, Richard L. ;
Jones, Glenville ;
Kovacs, Christopher S. ;
Mayne, Susan T. ;
Rosen, Clifford J. ;
Shapses, Sue A. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2011, 96 (01) :53-58
[10]
Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice [J].
Souberbielle, Jean-Claude ;
Body, Jean-Jacques ;
Lappe, Joan M. ;
Plebani, Mario ;
Shoenfeld, Yehuda ;
Wang, Thomas J. ;
Bischoff-Ferrari, Heike A. ;
Cavalier, Etienne ;
Ebeling, Peter R. ;
Fardellone, Patrice ;
Gandini, Sara ;
Gruson, Damien ;
Guerin, Alain P. ;
Heickendorff, Lene ;
Hollis, Bruce W. ;
Ish-Shalom, Sofia ;
Jean, Guillaume ;
von Landenberg, Philipp ;
Largura, Alvaro ;
Olsson, Tomas ;
Pierrot-Deseilligny, Charles ;
Pilz, Stefan ;
Tincani, Angela ;
Valcour, Andre ;
Zittermann, Armin .
AUTOIMMUNITY REVIEWS, 2010, 9 (11) :709-715