RECTAL ABSORPTION OF NITROGLYCERIN IN THE RAT - AVOIDANCE OF 1ST-PASS METABOLISM AS A FUNCTION OF RECTAL LENGTH EXPOSURE

被引：22

作者：

KAMIYA, A ^{[1
]}

OGATA, H ^{[1
]}

FUNG, HL ^{[1
]}

机构：

[1] SUNY BUFFALO, SCH PHARM, DEPT PHARMACEUT, BUFFALO, NY 14260 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1982年 / 71卷 / 06期

关键词：

D O I：

10.1002/jps.2600710606

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：621 / 624

页数：4

共 26 条

[1] VASODILATOR THERAPY IN ACUTE MYOCARDIAL-INFARCTION - COMPARISON OF SODIUM NITROPRUSSIDE AND NITROGLYCERIN [J].

ARMSTRONG, PW ;

WALKER, DC ;

BURTON, JR ;

PARKER, JO .

CIRCULATION, 1975, 52 (06) :1118-1122

[2] EFFECT OF METOCLOPRAMIDE ON NEONATAL GASTRIC-EMPTYING [J].

BLUMENTHAL, I ;

COSTALOS, C .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1977, 4 (02) :207-208

[3]

DEBOER AG, 1979, CLIN PHARMACOL THER, V26, P701

[4] RECTAL BIOAVAILABILITY OF LIDOCAINE IN RATS - ABSENCE OF SIGNIFICANT 1ST-PASS ELIMINATION [J].

DEBOER, AG ;

BREIMER, DD ;

PRONK, J ;

GUBBENSSTIBBE, JM .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (07) :804-807

[5]

DEBOER AG, 1981, DRUG ABSORPTION, P61

[6]

HIRSHLEIFER I, 1973, CURR THER RES CLIN E, V15, P158

[7] NITROGLYCERIN INFUSION DURING CORONARY-ARTERY SURGERY [J].

KAPLAN, JA ;

DUNBAR, RW ;

JONES, EL .

ANESTHESIOLOGY, 1976, 45 (01) :14-21

[8] GASTROINTESTINAL ABSORPTION OF ORGANIC NITRATES [J].

KRANTZ, JC ;

LEAKE, CD .

AMERICAN JOURNAL OF CARDIOLOGY, 1975, 36 (03) :407-408

[9] METABOLISM OF AND VASCULAR-RESPONSES TO GLYCERYL TRINITRATE IN EVISCERATED RAT [J].

LANG, S ;

JOHNSON, EM ;

NEEDLEMA.P .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (03) :422-&

[10] RELATIONSHIP BETWEEN INVIVO NITROGLYCERIN METABOLISM AND INVITRO ORGANIC NITRATE REDUCTASE-ACTIVITY IN RATS [J].

MAIER, GA ;

ARENA, C ;

FUNG, HL .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (04) :646-648

← 1 2 3 →