RECTAL ABSORPTION OF NITROGLYCERIN IN THE RAT - AVOIDANCE OF 1ST-PASS METABOLISM AS A FUNCTION OF RECTAL LENGTH EXPOSURE

被引：22

作者：

KAMIYA, A ^{[1
]}

OGATA, H ^{[1
]}

FUNG, HL ^{[1
]}

机构：

[1] SUNY BUFFALO, SCH PHARM, DEPT PHARMACEUT, BUFFALO, NY 14260 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1982年 / 71卷 / 06期

关键词：

D O I：

10.1002/jps.2600710606

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：621 / 624

页数：4

共 26 条

[21] EXTENSION OF THE BLOOD HALF-LIFE OF GLYCERYL TRINITRATE - INHIBITION OF GLUTATHIONE ORGANIC NITRATE ESTER REDUCTASE-ACTIVITY IN THE RAT AND GUINEA-PIG [J].

STEIN, RL ;

OBRIEN, JK ;

IRWIN, C ;

TOWNSENDPARCHMAN, JK ;

HUNTER, FE .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (12) :1807-1813

[22] OSMOTIC MINIPUMP - NEW TOOL IN STUDY OF STEADY-STATE KINETICS OF DRUG DISTRIBUTION AND METABOLISM [J].

STRUYKERBOUDIER, HAJ ;

SMITS, JF .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1978, 30 (09) :576-578

[23] CHRONIC INTRAVENOUS CANNULAS FOR RATS [J].

WEEKS, JR ;

DAVIS, JD .

JOURNAL OF APPLIED PHYSIOLOGY, 1964, 19 (03) :540-&

[24] ORAL NITROGLYCERIN AS A PROPHYLACTIC ANTIANGINAL DRUG - CLINICAL, PHYSIOLOGIC, AND STATISTICAL EVIDENCE OF EFFICACY BASED ON A 3-PHASE EXPERIMENTAL DESIGN [J].

WINSOR, T ;

BERGER, HJ .

AMERICAN HEART JOURNAL, 1975, 90 (05) :611-626

[25] IMPROVED GLC DETERMINATION OF PLASMA NITROGLYCERIN CONCENTRATIONS [J].

YAP, PSK ;

MCNIFF, EF ;

FUNG, HL .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (04) :582-584

[26] PHARMACOKINETICS OF NITROGLYCERIN IN RATS [J].

YAP, PSK ;

FUNG, HL .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1978, 67 (04) :584-586

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