BIACORE AS A TOOL IN ANTIBODY ENGINEERING

被引：54

作者：

MALMBORG, AC ^{[1
]}

BORREBAECK, CAK ^{[1
]}

机构：

[1] LUND UNIV,DEPT IMMUNOTECHNOL,S-22007 LUND,SWEDEN

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1995年 / 183卷 / 01期

关键词：

BIOSENSOR; PHAGE DISPLAY; KINETIC SELECTION; RECOMBINANT ANTIBODY; ANTIBODY LIBRARY;

D O I：

10.1016/0022-1759(95)00018-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The BIAcore biosensor provides a simple and rapid approach for analysing recombinant antibodies and phage displayed antibody libraries. In this review we describe the application of the biosensor in the screening of recombinant antibody fragments, kinetic selection of phage displayed antibodies, characterization and epitope mapping of monoclonal antibodies and their fragments.

引用

页码：7 / 13

页数：7

共 40 条

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