A NEW, GENERAL ENTRY TO 4-SUBSTITUTED INDOLES - SYNTHESIS OF (S)-(-)-PINDOLOL AND (+/-)-CHUANGXINMYCIN

被引:33
作者
ISHIBASHI, H
TABATA, T
HANAOKA, K
IRIYAMA, H
AKAMATSU, S
IKEDA, M
机构
[1] Kyoto Pharmaceutical University, Kyoto, 607, Misasagi, Yamashina
关键词
D O I
10.1016/0040-4039(93)85109-A
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new method for synthesis of 4-substituted indoles has been developed by using the 7-arylthio-6,7-dihydroindol-4(5H)one 5 as a common intermediate. The method was applied to the synthesis of (S)-(-)-pindolol (II) and (+/-)-chuangxinmycin (16).
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页码:489 / 492
页数:4
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