BIOSYNTHESIS OF THE CLERODANE FURANO-DITERPENE LACTONE SKELETON IN TINOSPORA-CORDIFOLIA

被引：17

作者：

AKHILA, A

RANI, K

THAKUR, RS

机构：

[1] Central Institute of Medicinal and Aromatic Plants, Lucknow

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 08期

关键词：

TINOSPORA-CORDIFOLIA; MENISPERMACEAE; CIS-CLERODANE FURANO-DITERPENE LACTONES; BIOSYNTHESIS;

D O I：

10.1016/0031-9422(91)85103-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isotope ratios in cis-clerodane furanoditerpene lactones labelled from [4R-H-3(1),2-C-14]MVA suggested two 1,2-hydrogen shifts and two 1,2-methyl shifts during the formation of the ring system of these diterpenes. Chemical degradation of clerodane diterpenoids radiolabelled from [2-C-14]MVA revealed that the gem-methyls of geranylgeranyl pyrophosphate (GGPP) retained their identity during the cyclization.

引用

页码：2573 / 2576

页数：4

共 14 条

[1]

AHMAD M, 1978, J BANGLADESH ACAD SC, V2, P25

[2] BIOGENETIC RELATIONSHIP OF POLYOXYGENATED DITERPENES IN COLEUS-FORSKOHLII [J].