REPRODUCTIVE FUNCTION IN EPILEPSY

被引：31

作者：

CRAMER, JA

JONES, EE

机构：

[1] YALE UNIV, SCH MED, DEPT NEUROL, NEW HAVEN, CT 06510 USA

[2] YALE UNIV, SCH MED, DEPT OBSTET & GYNECOL, DIV REPROD ENDOCRINOL, NEW HAVEN, CT 06510 USA

来源：

EPILEPSIA | 1991年 / 32卷

基金：

美国国家卫生研究院;

关键词：

EPILEPSY; ANTICONVULSANTS; DRUG-INDUCED ABNORMALITIES; HORMONES; REPRODUCTION; HYPOTHALAMUS; PITUITARY; MENSTRUAL CYCLE;

D O I：

10.1111/j.1528-1157.1991.tb05887.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The hypothalamic-pituitary-gonadal axis is a complex system within which both positive and negative feedback occur among its elements and higher brain systems. The occurrence of seizures and changes in the secretion of pituitary hormones can affect the feedback loop. Both seizures and antiepileptic drugs can affect the hypothalamic-pituitary-gonadal axis of males and females and cause changes in hormones and sexuality. Reproductive dysfunction has a social impact because of reduced fertility. Once conception occurs, live birth rates are not diminished. Prospective studies of men and women with epilepsy are needed.

引用

页码：S19 / S26

页数：8

共 61 条

[41]

MATTSON RH, 1981, EPILEPSIA, V22, P242

[42] USE OF ORAL-CONTRACEPTIVES BY WOMEN WITH EPILEPSY [J].

MATTSON, RH ;

CRAMER, JA ;

DARNEY, PD ;

NAFTOLIN, F .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1986, 256 (02) :238-240

[43] EFFECT OF THE REMOVAL OF INDIVIDUAL ANTIEPILEPTIC DRUGS ON ANTIPYRINE KINETICS, IN PATIENTS TAKING POLYTHERAPY [J].

PATSALOS, PN ;

DUNCAN, JS ;

SHORVON, SD .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1988, 26 (03) :253-259

[44] A COMPARATIVE-STUDY OF THE RELATIVE ENZYME INDUCING PROPERTIES OF ANTICONVULSANT DRUGS IN EPILEPTIC PATIENTS [J].

PERUCCA, E ;

HEDGES, A ;

MAKKI, KA ;

RUPRAH, M ;

WILSON, JF ;

RICHENS, A .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 18 (03) :401-410

[45] ACTIONS OF ESTROGENS AND PROGESTINS ON NERVE-CELLS [J].

PFAFF, DW ;

MCEWEN, BS .

SCIENCE, 1983, 219 (4586) :808-814

[46]

RIMERMAN RA, 1979, PHARMACOLOGIST, V21, P264

[47]

Rosciszewska D, 1975, Neurol Neurochir Pol, V9, P305

[48]

ROSCISZEWSKA D, 1976, NEUROL NEUROCHIR POL, V19, P597

[49]

Selye H, 1942, J LAB CLIN MED, V27, P1051

[50]

SONNEN AE, 1983, BR J CLIN PRACT S S, V27, P31

← 1 2 3 4 5 6 7 →