CIRCULATING ICAM-1 IN ALCOHOLIC LIVER-CIRRHOSIS

被引：7

作者：

MANDI, Y ^{[1
]}

NAGY, I ^{[1
]}

机构：

[1] ALBERT SZENT GYORGYI MED UNIV,DEPT MED 1,H-6701 SZEGED,HUNGARY

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1995年 / 106卷 / 03期

关键词：

ALCOHOLIC LIVER CIRRHOSIS; INTERCELLULAR ADHESION MOLECULE 1; SEPSIS;

D O I：

10.1159/000236859

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The intercellular adhesion molecule 1 (ICAM-1) level in the serum of patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbent assay. Circulating ICAM-1 was significantly elevated in the sera of all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade of the disease, but the highest levels of serum ICAM-1 (2,416 +/- 560 ng/ml) were measured in those patients who sufferred from superimposed acute alcoholic hepatitis. No elevated serum ICAM-1 level was found in the ascitic fluid of cirrhotic patients. The elevated serum levels of ICAM-1 in patients with alcoholic liver diseases may provide useful diagnostic or prognostic information.

引用

页码：302 / 304

页数：3