NITROUS-OXIDE VERSUS CARBON-DIOXIDE FOR SUPERCRITICAL FLUID EXTRACTION AND CHROMATOGRAPHY OF AMINES

Supercritical N2O has been evaluated and compared with supercritical CO2 as a solvent for supercritical fluid extraction of different amines. Supercritical H2O showed a higher solubility for amines and easily extracted both aliphatic and aromatic amines. The effect of substrate on extraction has been also examined. Supercritical N2O has been used as a mobile phase, with different diameter columns, for supercritical fluid chromatography. The total response of flame Ionization detection to supercritical N2O using packed capillary and open tubular capillary columns demonstrated the feasibility of flame ionization detection with N2O In a density programmed mode. © 1990, American Chemical Society. All rights reserved.