IGA NEPHROPATHY IN A CHILD WITH HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION

被引：12

作者：

TRACHTMAN, H

GAUTHIER, B

VINOGRAD, A

VALDERRAMA, E

机构：

[1] Department of Pediatrics, Schneider Children's Hospital, Long Island Campus for the Albert Einstein College of Medicine, New Hyde Park, 11042, NY

[2] Department of Pathology, Schneider Children's Hospital, Long Island Campus for the Albert Einstein College of Medicine, New Hyde Park, 11042, NY

来源：

PEDIATRIC NEPHROLOGY | 1991年 / 5卷 / 06期

关键词：

HUMAN IMMUNODEFICIENCY VIRUS TYPE-1; IGA NEPHROPATHY; HEMATURIA; KIDNEY BIOPSY;

D O I：

10.1007/BF00857885

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Infection with the human immunodeficiency virus type 1 (HIV-1) can cause a spectrum of renal disease, termed acquired immunodeficiency syndrome (AIDS) nephropathy. The most common clinical manifestations of kidney involvement in HIV-1-infected patients are protein-uria and/or nephrotic syndrome, and the histopathological pattern usually reveals focal segmental glomerulosclerosis. We describe an 8-year-old child with AIDS who presented with recurrent gross hematuria. A kidney biopsy demonstrated IgA nephropathy. This unique case indicates that the range of kidney disease in HIV-infected children may be broader than originally thought, and that these patients warrant a complete evaluation of any renal abnormality.

引用

页码：724 / 726

页数：3

共 13 条

[11]

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[12]

Czerkinsky C., Koopman W.J., Jackson S., Collins J.E., Crago S.S., Schrohenloher R.E., Julian B.A., Galla J.H., Mestecky J., Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathies, J Clin Invest, 77, pp. 1931-1938, (1986)

[13]

Emancipator S.N., Gallo G.R., Razaboni R., Lamm M.E., Experimental cholestasis promotes the deposition of glomerular IgA immune complexes, Am J Pathol, 113, pp. 19-26, (1983)

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