GENERAL AND EFFICIENT ROUTE TO PHOSPHORODITHIOATE ANALOGS OF NATURALLY-OCCURRING LIPIDS

被引：20

作者：

MARTIN, SF

WAGMAN, AS

机构：

[1] Department of Chemistry and Biochemistry, The University of Texas, Austin

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 22期

关键词：

D O I：

10.1021/jo00074a012

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general procedure has been developed for the efficient synthesis of lipid phosphorodithioate analogues 14a-f from 2-alkoxy-2-thio-1,3,2-dithiaphospholanes 13a-c, which are readily prepared from 2-chloro-1,3,2-dithiaphospholane (11) by sequential reaction with an alcohol and elemental sulfur.

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页码：5897 / 5899

页数：3

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