PRODUCTION OF GLYCOSYLATED PHYSIOLOGICALLY NORMAL HUMAN ALPHA-1-ANTITRYPSIN BY MOUSE FIBROBLASTS MODIFIED BY INSERTION OF A HUMAN ALPHA-1-ANTITRYPSIN CDNA USING A RETROVIRAL VECTOR

被引：75

作者：

GARVER, RI

CHYTIL, A

KARLSSON, S

FELLS, GA

BRANTLY, ML

COURTNEY, M

KANTOFF, PW

NIENHUIS, AW

ANDERSON, WF

CRYSTAL, RG

机构：

[1] NHLBI,CLIN HEMATOL BRANCH,BETHESDA,MD 20892

[2] NHLBI,MOLEC HEMATOL LAB,BETHESDA,MD 20892

[3] TRANSGENE SA,F-67000 STRASBOURG,FRANCE

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 04期

关键词：

D O I：

10.1073/pnas.84.4.1050

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1050 / 1054

页数：5

共 25 条

[1] PROSPECTS FOR HUMAN-GENE THERAPY [J].

ANDERSON, WF .

SCIENCE, 1984, 226 (4673) :401-409

[2] DELETIONS COVERING THE PUTATIVE PROMOTER REGION OF EARLY MESSENGER-RNAS OF SIMIAN-VIRUS-40 DO NOT ABOLISH T-ANTIGEN EXPRESSION [J].

BENOIST, C ;

CHAMBON, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07) :3865-3869

[3]

BLOBEL G, 1971, BIOMEMBRANES, P37

[4]

CASOLARO A, 1986, AM REV RESPIR DIS, V133, pA103

[5] HIGH-LEVEL PRODUCTION OF BIOLOGICALLY-ACTIVE HUMAN ALPHA-1-ANTITRYPSIN IN ESCHERICHIA-COLI [J].

COURTNEY, M ;

BUCHWALDER, A ;

TESSIER, LH ;

JAYE, M ;

BENAVENTE, A ;

BALLAND, A ;

KOHLI, V ;

LATHE, R ;

TOLSTOSHEV, P ;

LECOCQ, JP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (03) :669-673

[6] GENE-EXPRESSION IN MICE AFTER HIGH-EFFICIENCY RETROVIRAL-MEDIATED GENE-TRANSFER [J].

EGLITIS, MA ;

KANTOFF, P ;

GILBOA, E ;

ANDERSON, WF .

SCIENCE, 1985, 230 (4732) :1395-1398

[7]

Fagerhol M K, 1981, Adv Hum Genet, V11, P1

[8]

Gadek J., 1982, METABOLIC BASIS INHE, P1450

[9] ANTI-ELASTASES OF THE HUMAN ALVEOLAR STRUCTURES - IMPLICATIONS FOR THE PROTEASE-ANTIPROTEASE THEORY OF EMPHYSEMA [J].

GADEK, JE ;

FELLS, GA ;

ZIMMERMAN, RL ;

RENNARD, SI ;

CRYSTAL, RG .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (04) :889-898

[10] REPLACEMENT THERAPY OF ALPHA-1-ANTITRYPSIN DEFICIENCY - REVERSAL OF PROTEASE-ANTIPROTEASE IMBALANCE WITHIN THE ALVEOLAR STRUCTURES OF PIZ SUBJECTS [J].

GADEK, JE ;

KLEIN, HG ;

HOLLAND, PV ;

CRYSTAL, RG .

JOURNAL OF CLINICAL INVESTIGATION, 1981, 68 (05) :1158-1165

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