CHIRAL TITANIUM ALKOXIDES AS CATALYSTS FOR THE ENANTIOSELECTIVE REDUCTION OF KETONES WITH BORANES

被引：66

作者：

GIFFELS, G

DREISBACH, C

KRAGL, U

WEIGERDING, M

WALDMANN, H

WANDREY, C

机构：

[1] FORSCHUNGSZENTRUM JULICH, FORSCHUNGSZENTRUM, INST BIOTECHNOL, D-52425 JULICH, GERMANY

[2] UNIV KARLSRUHE, INST ORGAN CHEM, D-76128 KARLSRUHE, GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1995年 / 34卷 / 18期

关键词：

ASYMMETRIC SYNTHESES; CATALYSIS; CHIRAL AUXILIARIES; REDUCTIONS;

D O I：

10.1002/anie.199520051

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new application of chiral titanates such as 1 is the catalysis of the asymmetric addition of boranes to a ketocarbonyl group. Chiral alcohols are obtained in this reaction in good enantiomeric excesses ((S):(R) lies between 65:35 and 92:8). (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

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页码：2005 / 2006

页数：2

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