REACTIVITY OF QUINONE IMINE AND QUINONE DIIMINE METABOLITES OF THE ANTITUMOR DRUG AMSACRINE AND RELATED-COMPOUNDS TO NUCLEOPHILES

被引：16

作者：

LEE, HH ^{[1
]}

PALMER, BD ^{[1
]}

DENNY, WA ^{[1
]}

机构：

[1] UNIV AUCKLAND,SCH MED,CANC RES LAB,AUCKLAND,NEW ZEALAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1988年 / 53卷 / 26期

关键词：

D O I：

10.1021/jo00261a010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：6042 / 6047

页数：6

共 20 条

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[14]

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[15] DETECTION OF N-ACETYL-PARA-BENZOQUINONE IMINE PRODUCED DURING THE HYDROLYSIS OF THE MODEL PHENACETIN METABOLITE N-(PIVALOYLOXY)PHENACETIN [J].

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[16]

ROBBIE MA, UNPUB BIOCH PHARM

[17]

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[18]

SHOEMAKER DD, 1984, CANCER RES, V44, P1939

[19]

SHOEMAKER DD, 1982, DRUG METAB DISPOS, V10, P35

[20]

WONG A, 1984, BIOCHEMISTRY-US, V23, P1239

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