TRANSCELLULAR TRANSACTIVATION BY THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TAT PROTEIN

被引：112

作者：

HELLAND, DE ^{[1
]}

WELLES, JL ^{[1
]}

CAPUTO, A ^{[1
]}

HASELTINE, WA ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,DIV HUMAN RETROVIROL,44 BINNEY ST,BOSTON,MA 02115

来源：

JOURNAL OF VIROLOGY | 1991年 / 65卷 / 08期

关键词：

D O I：

10.1128/JVI.65.8.4547-4549.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The human immunodeficiency virus type 1 (HIV-1) transactivator (tat) protein produced in one cell activated HIV-1 promoter-directed gene expression in a second cell, provided the cells were in direct contact with one another. This observation suggests that the tat protein produced in HIV-1-infected cells has a physiological effect on neighboring cells.

引用

页码：4547 / 4549

页数：3

共 18 条

[11] MUTATIONAL ANALYSIS OF THE TRANS-ACTIVATION-RESPONSIVE REGION OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE-I LONG TERMINAL REPEAT
HAUBER, J
CULLEN, BR
[J]. JOURNAL OF VIROLOGY, 1988, 62 (03) : 673 - 679
[12] HUNG CH, 1990, ADV AP BIOT, V7, P183
[13] A DISCRETE ELEMENT 3' OF HUMAN IMMUNODEFICIENCY VIRUS-1 (HIV-1) AND HIV-2 MESSENGER-RNA INITIATION SITES MEDIATES TRANSCRIPTIONAL ACTIVATION BY AN HIV TRANS ACTIVATOR
JAKOBOVITS, A
SMITH, DH
JAKOBOVITS, EB
CAPON, DJ
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (06) : 2555 - 2561
[14] SEROLOGICAL CROSS-REACTIVITY BETWEEN ENVELOPE GENE-PRODUCTS OF TYPE-I AND TYPE-II HUMAN T-CELL LEUKEMIA-VIRUS
LEE, TH
COLIGAN, JE
MCLANE, MF
SODROSKI, JG
POPOVIC, M
WONGSTAAL, F
GALLO, RC
HASELTINE, W
ESSEX, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23): : 7579 - 7583
[15] INTRACELLULAR ASPECTS OF PROCESS OF PROTEIN-SYNTHESIS
PALADE, G
[J]. SCIENCE, 1975, 189 (4200) : 347 - 358
[16] THE LOCATION OF CIS-ACTING REGULATORY SEQUENCES IN THE HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE-III (HTLV-III/LAV) LONG TERMINAL REPEAT
ROSEN, CA
SODROSKI, JG
HASELTINE, WA
[J]. CELL, 1985, 41 (03) : 813 - 823
[17] A NOVEL SECRETORY PATHWAY FOR INTERLEUKIN-1-BETA, A PROTEIN LACKING A SIGNAL SEQUENCE
RUBARTELLI, A
COZZOLINO, F
TALIO, M
SITIA, R
[J]. EMBO JOURNAL, 1990, 9 (05) : 1503 - 1510
[18] TRANS-ACTING TRANSCRIPTIONAL REGULATION OF HUMAN T-CELL LEUKEMIA-VIRUS TYPE-III LONG TERMINAL REPEAT
SODROSKI, J
ROSEN, C
WONGSTAAL, F
SALAHUDDIN, SZ
POPOVIC, M
ARYA, S
GALLO, RC
HASELTINE, WA
[J]. SCIENCE, 1985, 227 (4683) : 171 - 173

← 1 2 →