Prefrontal CortexModulation during Anticipation ofWorking Memory Demands as Revealed by Magnetoencephalography

被引：23

作者：

Altamura, Mario ^{[1
,2
]}

Goldberg, Terry E. ^{[1
]}

Elvevag, Brita ^{[1
]}

Holroyd, Tom ^{[3
]}

Carver, Frederick W. ^{[3
]}

Weinberger, Daniel R. ^{[1
]}

Coppola, Richard ^{[1
,3
]}

机构：

[1] NIMH, Clin Brain Disorder Branch, Bldg 10,Rm 4S235, Bethesda, MD 20892 USA

[2] Univ Foggia, Dept Med Sci, Psychiat Unit, I-71100 Foggia, Italy

[3] NIH, MEG Core Facil, Bethesda, MD 20982 USA

来源：

INTERNATIONAL JOURNAL OF BIOMEDICAL IMAGING | 2010年 / 2010卷

关键词：

D O I：

10.1155/2010/840416

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

During the anticipation of task demands frontal control is involved in the assembly of stimulus- response mappings based on current goals. It is not clear whether prefrontal modulations occur in higher-order cortical regions, likely reflecting cognitive anticipation processes. The goal of this paper was to investigate prefrontal modulation during anticipation of upcoming working memory demands as revealed by magnetoencephalography (MEG). Twenty healthy volunteers underwent MEG while they performed a variation of the Sternberg Working Memory (WM) task. Beta band (14-30 Hz) SAM (Synthetic Aperture Magnetometry) analysis was performed. During the preparatory periods there was an increase in beta power (event-related synchronization) in dorsolateral prefrontal cortex (DLPFC) bilaterally, left inferior prefrontal gyrus, left parietal, and temporal areas. Our results provide support for the hypothesis that, during preparatory states, the prefrontal cortex is important for biasing higher order brain regions that are going to be engaged in the upcoming task.

引用

页数：10

共 49 条

[41] HIGH-SPEED SCANNING IN HUMAN MEMORY [J].

STERNBERG, S .

SCIENCE, 1966, 153 (3736) :652-+

[42] Functional coupling between frontal and parietal lobes during recognition memory [J].

Summerfield, C ;

Mangels, JA .

NEUROREPORT, 2005, 16 (02) :117-122

[43] Dissociable neural mechanisms for encoding predictable and unpredictable events [J].

Summerfield, Christopher ;

Mangels, Jennifer A. .

JOURNAL OF COGNITIVE NEUROSCIENCE, 2006, 18 (07) :1120-1132

[44] Models of human visual attention should consider trial-by-trial variability in preparatory neural signals [J].

Sylvester, Chad M. ;

d'Avossa, Giovanni ;

Corbetta, Maurizio .

NEURAL NETWORKS, 2006, 19 (09) :1447-1449

[45] Sustained and transient oscillatory responses in the gamma and beta bands in a visual short-term memory task in humans [J].

Tallon-Baudry, C ;

Kreiter, A ;

Bertrand, O .

VISUAL NEUROSCIENCE, 1999, 16 (03) :449-459

[46]

Tallon-Baudry C, 1998, J NEUROSCI, V18, P4244

[47] Functional imaging of postmovement beta event-related synchronization [J].

van Burik, M ;

Pfurtscheller, G .

JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 1999, 16 (04) :383-390

[48] The brainweb: Phase synchronization and large-scale integration [J].

Varela, F ;

Lachaux, JP ;

Rodriguez, E ;

Martinerie, J .

NATURE REVIEWS NEUROSCIENCE, 2001, 2 (04) :229-239

[49] Prestimulus cortical activity is correlated with speed of visuomotor processing [J].

Zhang, Yan ;

Wang, Xue ;

Bressler, Steven L. ;

Chen, Yonghong ;

Ding, Mingzhou .

JOURNAL OF COGNITIVE NEUROSCIENCE, 2008, 20 (10) :1915-1925

← 1 2 3 4 5 →