CHEMOENZYMATIC SYNTHESIS OF CARBOCYCLIC OXETANOCIN-A INVOLVING A NOVEL PHOTOCHEMICAL-REARRANGEMENT

被引：19

作者：

COTTERILL, IC

ROBERTS, SM

机构：

[1] Department of Chemistry, Exeter University, Exeter

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1992年 / 20期

关键词：

D O I：

10.1039/p19920002585

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The anti-herpes agent carbocyclic oxetanocin-A (-)-2 has been prepared from the bicyclic ketone 3 via resolution of the bromohydrin 4 (using an enzyme-catalysed trans-esterification reaction) and a photocatalysed rearrangement of the epoxide (+)-6 to the lactone (+)-7.

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页码：2585 / 2586

页数：2

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