STRUCTURE-ACTIVITY-RELATIONSHIPS OF SYNTHETIC DIOSGENYL DIGLYCOSIDES

被引：9

作者：

TAKECHI, M ^{[1
]}

SHIMADA, S ^{[1
]}

TANAKA, Y ^{[1
]}

机构：

[1] SHIMADA PHARMACEUT INST,SUMINOE KU,OSAKA 559,JAPAN

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 09期

关键词：

STRUCTURE-ACTIVITY RELATIONSHIPS; HEMOLYSIS; ANTIFUNGAL ACTIVITY; SYNTHETIC DIGLYCOSIDES; DIOSGENIN; SAPONIN;

D O I：

10.1016/0031-9422(92)83496-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The haemolytic and antifungal activities of six synthetic diosgenyl diglycosides and diosgenyl maltotrioside were compared with each other and with those of the parent glucoside. In general, the haemolytic activity of each of these glycosides was higher than, and the antifungal activity as strong as, that of the glucoside. However, both activities of the lactoside were much lower than those of the others.

引用

页码：3280 / 3281

页数：2

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