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STRUCTURAL REQUIREMENTS FOR THE DEVELOPMENT OF POTENT N-METHYL-D-ASPARTIC ACID (NMDA) RECEPTOR ANTAGONISTS

被引：49
作者：
BIGGE, CF
机构：
来源：
BIOCHEMICAL PHARMACOLOGY | 1993年 / 45卷 / 08期
关键词：
D O I：
10.1016/0006-2952(93)90294-7
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1547 / 1561
页数：15
相关论文
共 84 条
  • [71] SILLS MA, 1989, MOL PHARMACOL, V36, P160
  • [72] ENANTIOMERS OF HA-966 (3-AMINO-1-HYDROXYPYRROLID-2-ONE) EXHIBIT DISTINCT CENTRAL NERVOUS-SYSTEM EFFECTS - (+)-HA-966 IS A SELECTIVE GLYCINE N-METHYL-D-ASPARTATE RECEPTOR ANTAGONIST, BUT (-)-HA-966 IS A POTENT GAMMA-BUTYROLACTONE-LIKE SEDATIVE
    SINGH, L
    DONALD, AE
    FOSTER, AC
    HUTSON, PH
    IVERSEN, LL
    IVERSEN, SD
    KEMP, JA
    LEESON, PD
    MARSHALL, GR
    OLES, RJ
    PRIESTLEY, T
    THORN, L
    TRICKLEBANK, MD
    VASS, CA
    WILLIAMS, BJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (01) : 347 - 351
  • [73] STRUCTURAL REQUIREMENTS FOR ACTIVATION OF THE GLYCINE RECEPTOR THAT MODULATES THE N-METHYL-D-ASPARTATE OPERATED ION CHANNEL
    SNELL, LD
    MORTER, RS
    JOHNSON, KM
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 156 (01) : 105 - 110
  • [74] SYNTHESIS OF CIS-4-AMIDO AND TRANS-4-AMIDO 2-CARBOXYTETRAHYDROQUINOLINES, HIGH-AFFINITY LIGANDS AT THE GLYCINE SITE OF THE NMDA RECEPTOR
    STEVENSON, GI
    LEESON, PD
    ROWLEY, M
    SANDERSON, I
    STANSFIELD, I
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1992, 2 (05) : 371 - 374
  • [75] PHOSPHORYLATION OF LIGAND-GATED ION CHANNELS - A POSSIBLE MODE OF SYNAPTIC PLASTICITY
    SWOPE, SL
    MOSS, SJ
    BLACKSTONE, CD
    HUGANIR, RL
    [J]. FASEB JOURNAL, 1992, 6 (08) : 2514 - 2523
  • [76] SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF A SERIES OF DIBENZO[A,D]CYCLOALKENIMINES AS N-METHYL-D-ASPARTATE ANTAGONISTS
    THOMPSON, WJ
    ANDERSON, PS
    BRITCHER, SF
    LYLE, TA
    THIES, JE
    MAGILL, CA
    VARGA, SL
    SCHWERING, JE
    LYLE, PA
    CHRISTY, ME
    EVANS, BE
    COLTON, CD
    HOLLOWAY, MK
    SPRINGER, JP
    HIRSHFIELD, JM
    BALL, RG
    AMATO, JS
    LARSEN, RD
    WONG, EHF
    KEMP, JA
    TRICKLEBANK, MD
    SINGH, L
    OLES, R
    PRIESTLY, T
    MARSHALL, GR
    KNIGHT, AR
    MIDDLEMISS, DN
    WOODRUFF, GN
    IVERSEN, LL
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (02) : 789 - 808
  • [77] SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 1-PHENYLCYCLOHEXYLAMINE ANALOGS
    THURKAUF, A
    DECOSTA, B
    YAMAGUCHI, S
    MATTSON, MV
    JACOBSON, AE
    RICE, KC
    ROGAWSKI, MA
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (05) : 1452 - 1458
  • [78] SYNTHESIS, ABSOLUTE-CONFIGURATION, AND MOLECULAR MODELING STUDY OF ETOXADROL, A POTENT PHENCYCLIDINE-LIKE AGONIST
    THURKAUF, A
    ZENK, PC
    BALSTER, RL
    MAY, EL
    GEORGE, C
    CARROLL, FI
    MASCARELLA, SW
    RICE, KC
    JACOBSON, AE
    MATTSON, MV
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (12) : 2257 - 2263
  • [79] REGULATION OF KAINATE RECEPTORS BY CAMP-DEPENDENT PROTEIN-KINASE AND PHOSPHATASES
    WANG, LY
    SALTER, MW
    MACDONALD, JF
    [J]. SCIENCE, 1991, 253 (5024) : 1132 - 1135
  • [80] MODELING OF COMPETITIVE PHOSPHONO AMINO-ACID NMDA RECEPTOR ANTAGONISTS
    WHITTEN, JP
    HARRISON, BL
    WEINTRAUB, HJR
    MCDONALD, IA
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (09) : 1509 - 1514
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