STUDIES ON THE SYNTHESIS OF SCOPARIC ACID-A AND RELATED LABDANE DITERPENOIDS - SYNTHESIS OF (E)-6-BETA-HYDROXLABDA-8-(17),13-DIEN-15-OIC ACID

被引：8

作者：

ABAD, A

ARNO, M

AGULLO, C

CUNAT, AC

MESEGUER, B

ZARAGOZA, RJ

机构：

[1] Departament de Química Orgánica, Universitat de València, 46100, Burjassot, València

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 12期

关键词：

D O I：

10.1021/np50102a016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A general strategy fbr a successful approach to labdanes of the type 3-5 is described. This methodology, which makes use of the known Eschenmoser fragmentation of 9, 1,3-oxidative rearrangement of allylic tertiary alcohol 14, and photochemical double bond isomerization of allylic acetate 17 as key synthetic steps, is used to prepare optically pure labdane 5 from readily available (+)-podocarpenone 8.

引用

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页码：2133 / 2141

页数：9

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