THE AT2 ANGIOTENSIN RECEPTOR SUBTYPE PREDOMINATE SIN THE 18 DAY GESTATION FETAL-RAT BRAIN

被引：44

作者：

COOK, VI ^{[1
]}

GROVE, KL ^{[1
]}

MCMENAMIN, KM ^{[1
]}

CARTER, MR ^{[1
]}

HARDING, JW ^{[1
]}

SPETH, RC ^{[1
]}

机构：

[1] WASHINGTON STATE UNIV,COLL VET MED,DEPT VET & COMPARAT ANAT PHARMACOL & PHYSIOL,PULLMAN,WA 99164

来源：

BRAIN RESEARCH | 1991年 / 560卷 / 1-2期

关键词：

ANGIOTENSIN RECEPTOR; SUBTYPE; BRAIN; RAT FETUS;

D O I：

10.1016/0006-8993(91)91254-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The angiotensin II receptor subtype-specific antagonists Dup 753 (AT1) and PD 123177 (AT2) were used to characterize the angiotensin II receptor subtypes present in 18 day gestation fetal Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rat brain using in vitro receptor autoradiography. The AT2 subtype was predominant in the brain of both rat strains, even in areas that display predominantly the AT1 subtype in the adult rat brain.

引用

页码：334 / 336

页数：3

共 21 条

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