HLA CLASS-I AND CLASS-II ANTIGENS IN SOUTH-AFRICAN BLACKS WITH GRAVES-DISEASE

被引：23

作者：

OMAR, MAK

HAMMOND, MG

DESAI, RK

MOTALA, AA

ABOO, N

SEEDAT, MA

机构：

[1] UNIV NATAL,NATAL INST IMMUNOL,CONGELLA 4013,SOUTH AFRICA

[2] UNIV NATAL,DEPT CHEM PATHOL,CONGELLA 4013,SOUTH AFRICA

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1990年 / 54卷 / 01期

关键词：

D O I：

10.1016/0090-1229(90)90009-F

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A study was done to evaluate the relationship between Graves' disease and the HLA system in South African Blacks of Zulu descent. One hundred and three patients with Graves' disease and 1416 control subjects were typed for HLA A, B, and C antigens while HLA DR antigens were done on 63 of the former and 330 of the latter. There was a significant increase in the frequency of HLA DR3 in patients compared to control subjects (57.1% vs 36.1%; P corrected = 0.014). A relationship was also seen at the DRI locus (14.3% vs 4.6%; P corrected = 0.023). © 1990.

引用

页码：98 / 102

页数：5

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