ONE-POT SYNTHESIS OF NOVEL SPIRO-ANNELATED PYRROLE-CONTAINING HETEROCYCLIC-SYSTEMS FROM SUITABLE SYNTHONS

被引：9

作者：

ARTICO, M ^{[1
]}

MASSA, S ^{[1
]}

MAI, A ^{[1
]}

SILVESTRI, R ^{[1
]}

STEFANCICH, G ^{[1
]}

机构：

[1] UNIV TRIESTE,DIPARTIMENTO SCI FARMACEUT,I-34127 TRIESTE,ITALY

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 01期

关键词：

D O I：

10.1002/jhet.5570290144

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New tetracyclic systems containing a pyrrolobenzodiazepine 5 or a pyrrolobenzotriazepine 6 moiety bounded by a spiro linkage to the piperidine nucleus are described. They have been synthesized by a simple reaction involving the interaction between proper aromatic amines and 4-oxopiperidines substituted or not at the 1-position in the presence of maleic acid as a catalyst. The synthesis of spiropyrrolo[1,2-a]quinoxaline-2,4'-piperidine 7 and its 1'-acyl derivatives by the same procedure is also reported.

引用

页码：241 / 245

页数：5

共 16 条

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