ASYMMETRIC-SYNTHESIS OF THE ENANTIOMERS OF THE DIARYLCARBINOL (1R)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE AND (1S)-1-(1-HYDROXYPHENYLMETHYL)-2-HYDROXYBENZENE

被引：27

作者：

DAVIES, SG

HUME, WE

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 02期

关键词：

D O I：

10.1039/c39950000251

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(1S)-1-Phenethyl(phenyl chromium tricarbonyl) ether (-)-4 undergoes completely stereoselective ortho-deprotonation with the thus formed carbanion being converted by the complementary sequences, benzoylation/hydride reduction and formylation/PhMgBr addition, to generate after decomplexation and deprotection the homochiral diarylcarbinols (-)-(1R)- and (+)-(1S)-1-(1-hydroxyphenylmethyl)-2-hydroxybenzene 1, respectively.

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页码：251 / 252

页数：2

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