TAXOIDS FROM THE BARKS OF TAXUS-WALLICHIANA

被引：28

作者：

ZHANG, JZ

FANG, QC

LIANG, XT

HE, CH

KONG, M

HE, WY

JIN, XL

机构：

[1] CHINESE ACAD MED SCI,INST MAT MED,BEIJING 100000050,PEOPLES R CHINA

[2] BEIJING UNION MED COLL,BEIJING 100000050,PEOPLES R CHINA

来源：

PHYTOCHEMISTRY | 1995年 / 40卷 / 03期

关键词：

TAXUS WALLICHIANA; TAXACEAE; TAXOID; DITERPENOIDS; BARK;

D O I：

10.1016/0031-9422(95)00370-M

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Two new taxane diterpenoids, 1-hydroxy-2-deacetoxytaxinine J and 7,2'-bisdeacetoxyaustrospicatine, were isolated from the barks of Taxus wallichiana together with 13 known compounds, including taxol. Their structures were elucidated and identified by spectroscopic methods. The structure of 7,2'-bisdeacetoxyaustrospicatine was further confirmed by X-ray crystallographic analysis.

引用

页码：881 / 884

页数：4

共 17 条

[1]

14-BETA-HYDROXY-10-DEACETYLBACCATIN-III, A NEW TAXANE FROM HIMALAYAN YEW (TAXUS-WALLICHIANA ZUCC) [J].

APPENDINO, G ;

GARIBOLDI, P ;

GABETTA, B ;

PACE, R ;

BOMBARDELLI, E ;

VITERBO, D .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (21) :2925-2929

[2]

APPENDINO G, 1993, FITOTERAPIA S1, V4, P37

[3]

THE CHEMISTRY AND OCCURRENCE OF TAXANE DERIVATIVES .5. TAXANES FROM THE NEEDLES OF TAXUS-WALLICHIANA [J].

BARBONI, L ;

GARIBOLDI, P ;

TORREGIANI, E ;

APPENDINO, G ;

GABETTA, B ;

ZINI, G ;

BOMBARDELLI, E .

PHYTOCHEMISTRY, 1993, 33 (01) :145-150

[4]

Chen W. M., 1994, Acta Pharmaceutica Sinica, V29, P207

[5]

ETTOUATI L, 1988, B SOC CHIM FR, P749

[6]

A REINVESTIGATION OF THE TAXOL CONTENT OF HIMALAYAN TAXUS-WALLICHIANA ZUCC AND A REVISION OF THE STRUCTURE OF BREVIFOLIOL [J].

GEORG, GI ;

GOLLAPUDI, SR ;

GRUNEWALD, GL ;

GUNN, CW ;

HIMES, RH ;

RAO, BK ;

LIANG, XZ ;

MIRHOM, YW ;

MITSCHER, LA ;

VANDERVELDE, DG ;

YE, QM .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1993, 3 (06) :1345-1348

[7]

LIANG JY, 1988, ACTA CHIM SINICA, V46, P1053

[8]

19-HYDROXYBACCATIN-III, 10-DEACETYLCEPHALOMANNINE, AND 10-DEACETYLTAXOL - NEW ANTI-TUMOR TAXANES FROM TAXUS-WALLICHIANA [J].

MCLAUGHLIN, JL ;

MILLER, RW ;

POWELL, RG ;

SMITH, CR .

JOURNAL OF NATURAL PRODUCTS, 1981, 44 (03) :312-319

[9]

LIGNANS FROM TAXUS-WALLICHIANA [J].

MILLER, RW ;

MCLAUGHLIN, JL ;

POWELL, RG ;

PLATTNER, RD ;

WEISLEDER, D ;

SMITH, CR .

JOURNAL OF NATURAL PRODUCTS, 1982, 45 (01) :78-82

[10]

ANTI-LEUKEMIC ALKALOIDS FROM TAXUS-WALLICHIANA ZUCC [J].

MILLER, RW ;

POWELL, RG ;

SMITH, CR ;

ARNOLD, E ;

CLARDY, J .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (07) :1469-1474

← 1 2 →