DIETARY SATURATED FATTY-ACIDS (12-0, 14-0, 16-0) DIFFER IN THEIR IMPACT ON PLASMA-CHOLESTEROL AND LIPOPROTEINS IN NONHUMAN-PRIMATES

被引：177

作者：

HAYES, KC ^{[1
]}

PRONCZUK, A ^{[1
]}

LINDSEY, S ^{[1
]}

DIERSENSCHADE, D ^{[1
]}

机构：

[1] MEAD JOHNSON NUTR GRP,EVANSVILLE,IN

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1991年 / 53卷 / 02期

关键词：

DIETARY FATTY ACIDS; SATURATED FAT; SATURATED FATTY ACIDS; PALMITIC ACID; LIPOPROTEINS; PLASMA CHOLESTEROL; MONKEYS;

D O I：

10.1093/ajcn/53.2.491

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Three species of monkey (rhesus, cebus, and squirrel) were rotated through five purified diets containing 31% energy as various fat blends (P:S between 0.1 and 1.0) for 12-wk periods to compare the impact of specific dietary fatty acids on plasma lipids and lipoproteins. As 12:0 + 14:0 was replaced by 16:0, a significant decrease occurred in total and LDL cholesterol, whereas slight increases in total cholesterol and the LDL-HDL ratio occurred when 16:0 replaced 18:2. Hegsted and Keys regression equations provided a good fit for the observed data, but the predicted total cholesterol response was perfect (r = 0.995) for both equations when 16:0 was considered neutral. Thus, under these conditions 16:0 was less cholesterolemic than 12:0 + 14:0 and only slightly cholesterolemic compared with 18:2.

引用

页码：491 / 498

页数：8

共 37 条

[21] SERUM CHOLESTEROL RESPONSE TO CHANGES IN DIET .4. PARTICULAR SATURATED FATTY ACIDS IN DIET [J].