TRANSDUCTION OF RECEPTOR SIGNAL INTO MODULATION OF EFFECTOR ACTIVITY BY G PROTEINS - THE 1ST 20 YEARS OR SO

被引:84
作者
BIRNBAUMER, L
机构
[1] BAYLOR UNIV, DIV NEUROSCI, HOUSTON, TX 77030 USA
[2] BAYLOR UNIV, DEPT MOLEC PHYSIOL & BIOPHYS, HOUSTON, TX 77030 USA
关键词
Adenylyl cyclase; G proteins; GTPase; Hormone action; Receptors; Signal transduction;
D O I
10.1096/fasebj.4.14.2172060
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
G proteins are central to the transduction of many receptor signals. I review the ''firsts'' that have led to our current knowledge and delineate some of the issues being investigated in several laboratories worldwide.
引用
收藏
页码:3178 / 3188
页数:11
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