SLEEP-WAKEFULNESS PATTERNS IN THE HELPLESS RAT

被引：102

作者：

ADRIEN, J

DUGOVIC, C

MARTIN, P

机构：

[1] JANSSEN RES FDN,BEERSE,BELGIUM

[2] CHU PITIE SALPETRIERE,DEPT PHARMACOL,F-75013 PARIS,FRANCE

来源：

PHYSIOLOGY & BEHAVIOR | 1991年 / 49卷 / 02期

关键词：

HELPLESSNESS; EXPERIMENTAL MODELS OF DEPRESSION; INESCAPABLE SHOCKS; STRESS; AVOIDANCE CONDITIONING; SHUTTLE-BOX TRAINING; ESCAPE DEFICIT; SLEEP-WAKEFULNESS PATTERNS; PARADOXICAL SLEEP; CIRCADIAN RHYTHM;

D O I：

10.1016/0031-9384(91)90041-L

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Sleep-wakefulness patterns were analyzed during a 15-day period in the rat, in relation to induction of helplessness. After a session of inescapable electric footshocks, rats did exhibit escape deficits in avoidance conditioning as classically described, and their spontaneous sleep-wakefulness patterns were not different from those of controls. However, reduced PS latency and increased PS amounts were observed in the helpless group after shuttle-box sessions, especially during the initial period after the induction of helplessness. Such modifications of PS latency and PS amounts are evocative of the sleep impairments classically observed in endogenous depression.

引用

页码：257 / 262

页数：6