DIRECT MEASUREMENT OF OCTANOL-WATER PARTITION-COEFFICIENTS BY HIGH-PRESSURE LIQUID-CHROMATOGRAPHY

被引：200

作者：

MIRRLEES, MS ^{[1
]}

MOULTON, SJ ^{[1
]}

MURPHY, CT ^{[1
]}

TAYLOR, PJ ^{[1
]}

机构：

[1] ICI LTD,DIV PHARM,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1976年 / 19卷 / 05期

关键词：

D O I：

10.1021/jm00227a008

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：615 / 619

页数：5

相关论文

共 33 条

[11] DETERMINATION OF PARTITION-COEFFICIENT DATA USING AKUFVE METHOD
DAVIS, SS
ELSON, G
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1974, 26 : P90 - P90
[12] DEARDEN JC, 1972, J PHARM PHARMACOL, V24, pP115
[13] DRABER W, 1972, Z NATURFORSCH PT B, VB 27, P159
[14] NEW SUBSTITUENT CONSTANT PI DERIVED FROM PARTITION COEFFICIENTS
FUJITA, T
HANSCH, C
IWASA, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) : 5175 - &
[15] PAPER CHROMATOGRAPHY AND CHEMICAL STRUCTURE .8. HYPERCONJUGATION
GREEN, J
MARCINKIEWICZ, S
[J]. JOURNAL OF CHROMATOGRAPHY, 1963, 10 (03): : 389 - &
[16] HAGGERTY WJ, 1974, RES DEV, V25, P30
[17] HAGGERTY WJ, TO BE PUBLISHED
[18] LINEAR RELATIONSHIPS BETWEEN LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS
HANSCH, C
DUNN, WJ
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (01) : 1 - &
[19] EFFECT OF INTRAMOLECULAR HYDROPHOBIC BONDING ON PARTITION COEFFICIENTS
HANSCH, C
ANDERSON, SM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (08) : 2583 - &
[20] A QUANTITATIVE APPROACH TO BIOCHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS
HANSCH, C
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1969, 2 (08) : 232 - &

← 1 2 3 4 →