MATHEMATICAL-MODEL FOR LACTIC-ACID PRODUCTION FROM LACTOSE IN BATCH CULTURE - MODEL DEVELOPMENT AND SIMULATION

被引：33

作者：

AMRANE, A ^{[1
]}

PRIGENT, Y ^{[1
]}

机构：

[1] UNIV RENNES 1,IUT,DEPT CHIM,PROC SEPARAT LAB,BP 1144,F-35014 RENNES,FRANCE

来源：

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY | 1994年 / 60卷 / 03期

关键词：

LACTIC ACID FERMENTATION; MODEL; KINETICS; BATCH; WHEY PERMEATE;

D O I：

10.1002/jctb.280600303

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The models available to describe lactic acid production do not seem to fit the experimental data very well, especially at the end of batch cultures. From a careful analysis of batch data, an unstructured model of the process has been derived, in which the specific growth rate variations and lactic acid concentration with time have been described by complemented logistic functions. Also, an additional term has been introduced into the Luedeking-Piret expression, taking into account the reduction in rate of lactic acid production observed at very low growth rate.

引用

页码：241 / 246

页数：6

共 19 条

[1] THE PRODUCTION OF LACTIC-ACID FROM WHEY PERMEATE BY LACTOBACILLUS-HELVETICUS [J].

AESCHLIMANN, A ;

VONSTOCKAR, U .

BIOTECHNOLOGY LETTERS, 1989, 11 (03) :195-200

[2]

AMRANE A, 1994, APPL MICROBIOL BIOT, V40, P644, DOI [10.1007/BF00173322, 10.1007/s002530050043]

[3]

AYROULETMARTIN M, 1979, ANN TECHNOL AGR, V28, P333

[4]

BELHOCINE D, 1987, THESIS U RENNES 1 RE

[5] LACTOSE CONTINUOUS FERMENTATION WITH CELLS RECYCLED BY ULTRAFILTRATION AND LACTATE SEPARATION BY ELECTRODIALYSIS - MODEL IDENTIFICATION [J].

DERAUCOURT, A ;

GIRARD, D ;

PRIGENT, Y ;

BOYAVAL, P .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1989, 30 (05) :528-534

[6] KINETIC STUDIES OF LACTIC-ACID FERMENTATION IN BATCH AND CONTINUOUS CULTURES [J].

HANSON, TP ;

TSAO, GT .

BIOTECHNOLOGY AND BIOENGINEERING, 1972, 14 (02) :233-&

[7]

Herbert D., 1971, METHODS ENZYMOL, V5, P266, DOI 10.1016/S0580-9517(08)70641-X

[8] LACTIC-ACID PRODUCTION BY BATCH FERMENTATION OF WHEY PERMEATE - A MATHEMATICAL-MODEL [J].

LEH, MB ;

CHARLES, M .

JOURNAL OF INDUSTRIAL MICROBIOLOGY, 1989, 4 (01) :65-70

[9]

Levenspiel O, 1999, CHEM REACTION ENG, Vthird

[10] TRANSIENT AND STEADY STATES IN CONTINUOUS FERMENTATION - THEORY AND EXPERIMENT [J].

LUEDEKING, R ;

PIRET, EL .

JOURNAL OF BIOCHEMICAL AND MICROBIOLOGICAL TECHNOLOGY AND ENGINEERING, 1959, 1 (04) :431-459

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