ALPHA-TRIFLUOROMETHYL SUBSTITUTED ALPHA-AMINO-ACIDS AND ALPHA-HYDROXYACIDS WITH ORGANOMETALLIC MOIETIES IN THE SIDE-CHAIN

被引:10
作者
SEWALD, N [1 ]
GAA, K [1 ]
BURGER, K [1 ]
机构
[1] TECH UNIV MUNICH, INST ORGAN CHEM, LICHTENBERGSTR 4, W-8046 GARCHING, GERMANY
关键词
D O I
10.1002/hc.520040220
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Several strategies for the synthesis of alpha-trifluoromethyl substituted alpha-aminoacids and alpha-hydroxyacids with organometallic moieties in the side chain are described. The preparative potential of organometallic substituents (organosilicon, organotin, and organocobalt moieties) offers a convenient methodology for the synthesis of highly functionalized alpha-aminoacid and alpha-hydroxyacid derivatives.
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收藏
页码:253 / 258
页数:6
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