HUMAN PROGESTERONE-RECEPTOR COMPLEXED WITH THE ANTAGONIST RU-486 BINDS TO HORMONE RESPONSE ELEMENTS IN A STRUCTURALLY ALTERED FORM

被引：133

作者：

ELASHRY, D ^{[1
]}

ONATE, SA ^{[1
]}

NORDEEN, SK ^{[1
]}

EDWARDS, DP ^{[1
]}

机构：

[1] UNIV COLORADO,HLTH SCI CTR,DEPT PATHOL B216,4200 E 9TH ST,DENVER,CO 80262

来源：

MOLECULAR ENDOCRINOLOGY | 1989年 / 3卷 / 10期

关键词：

D O I：

10.1210/mend-3-10-1545

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1545 / 1558

页数：14

共 34 条

[11] RECEPTORS BOUND TO ANTIPROGESTIN FORM ABORTIVE COMPLEXES WITH HORMONE RESPONSIVE ELEMENTS [J].

GUIOCHONMANTEL, A ;

LOOSFELT, H ;

RAGOT, T ;

BAILLY, A ;

ATGER, M ;

MISRAHI, M ;

PERRICAUDET, M ;

MILGROM, E .

NATURE, 1988, 336 (6200) :695-698

[12] INHIBITION OF GLUCOCORTICOSTEROID ACTION IN CULTURED L-929 MOUSE FIBROBLASTS BY RU486, A NEW ANTI-GLUCOCORTICOSTEROID OF HIGH-AFFINITY FOR THE GLUCOCORTICOSTEROID RECEPTOR [J].

JUNGTESTAS, I ;

BAULIEU, EE .

EXPERIMENTAL CELL RESEARCH, 1983, 147 (01) :177-182

[13] THE ESTROGEN-RECEPTOR BINDS TIGHTLY TO ITS RESPONSIVE ELEMENT AS A LIGAND-INDUCED HOMODIMER [J].

KUMAR, V ;

CHAMBON, P .

CELL, 1988, 55 (01) :145-156

[14]

MANTIATIS T, 1982, MOL CLONING LABORATO

[15] RU-38486 - POTENT ANTIGLUCOCORTICOID ACTIVITY CORRELATED WITH STRONG BINDING TO THE CYTOSOLIC GLUCOCORTICOID RECEPTOR FOLLOWED BY AN IMPAIRED ACTIVATION [J].

MOGUILEWSKY, M ;

PHILIBERT, D .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1984, 20 (01) :271-276

[16] TRANSFORMATION OF CALF UTERINE PROGESTERONE-RECEPTOR - ANALYSIS OF THE PROCESS WHEN RECEPTOR IS BOUND TO PROGESTERONE AND RU38486 [J].

MOUDGIL, VK ;

HURD, C .

BIOCHEMISTRY, 1987, 26 (16) :4993-5001

[17] ANTIPROGESTIN-RECEPTOR COMPLEXES - DIFFERENCES IN THE INTERACTION OF THE ANTIPROGESTIN-RU38,486 AND THE PROGESTIN-R5020 WITH THE PROGESTERONE-RECEPTOR OF HUMAN-BREAST CANCER-CELLS [J].

MULLICK, A ;

KATZENELLENBOGEN, BS .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 135 (01) :90-97

[18] A RAPID, SENSITIVE, AND INEXPENSIVE ASSAY FOR CHLORAMPHENICOL ACETYLTRANSFERASE [J].

NORDEEN, SK ;

GREEN, PP ;

FOWLKES, DM .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1987, 6 (02) :173-178

[19]

NORDEEN SK, MOL ENDOCRINOL, V3, P1270

[20]

Philibert D., 1984, ADRENAL STEROID ANTA, P77

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