REMOTE DIANIONS .5. SYNTHESIS OF DELTA-CONICEINE

被引:16
作者
GREEN, DLC [1 ]
THOMPSON, CM [1 ]
机构
[1] LOYOLA UNIV,DEPT CHEM,CHICAGO,IL 60626
关键词
D O I
10.1016/S0040-4039(00)93425-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A total synthesis of (+/-) delta-coniceine from 1,4-butanediol is herein reported. A pivotal transformation of the synthesis involves the addition of the dianion of 4-(phenylsulfonyl)butanoic acid to an activated imine followed by subsequent cyclization to form a substituted piperidone intermediate.
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页码:5051 / 5054
页数:4
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