THE FIRST TOTAL SYNTHESES OF TAXOL

被引：16

作者：

WESSJOHANN, L

机构：

[1] Institut für Organische Chemie, Universität München, D-80333

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 09期

关键词：

D O I：

10.1002/anie.199409591

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A milestone in natural product chemistry is the first total synthesis of taxol achieved independently of each other by the groups of R. A. Holton and K. C. Nicolaou. Taxol is at present the most promising anti‐cancer agent, and its synthesis is extremely demanding. It is highly unlikely that this climax will be the end of probably the greatest worldwide effort yet to synthesize a single compound. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：959 / 961

页数：3

共 12 条

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