FORMATION OF PARA-HYDROXYBENZOIC ACID FROM PARA-COUMARIC ACID BY CELL-FREE-EXTRACT OF LITHOSPERMUM-ERYTHRORHIZON CELL-CULTURES

被引：57

作者：

YAZAKI, K ^{[1
]}

HEIDE, L ^{[1
]}

TABATA, M ^{[1
]}

机构：

[1] KYOTO UNIV,FAC PHARMACEUT SCI,DEPT PHARMACOGNOSY,KYOTO 606,JAPAN

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 07期

关键词：

LITHOSPERMUM-ERYTHRORHIZON; BORAGINACEAE; CELL CULTURE; BIOSYNTHESIS; PARA-HYDROXYBENZOIC ACID; PARA-COUMARIC ACID; PARA-HYDROXYBENZALDEHYDE; SHIKONIN;

D O I：

10.1016/0031-9422(91)83620-Z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The enzymatic formation of p-hydroxybenzoic acid from p-coumaric acid has been detected in cell free extracts of Lithospermum erythrorhizon cell cultures. In the absence of NAD, p-hydroxybenzaldehyde is formed instead of p-hydroxybenzoic acid. The reaction is specific to p-coumaric acid. In addition, a p-hydroxybenzaldehyde dehydrogenase activity is also found. The results suggest that the reaction mechanism is non-oxidative.

引用

页码：2233 / 2236

页数：4

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