STRUCTURAL STUDIES OF THE PUTATIVE O-SPECIFIC POLYSACCHARIDE OF ACINETOBACTER-BAUMANNII O2 CONTAINING 3,6-DIDEOXY-3-N-(D-3-HYDROXYBUTYRYL)AMINO-D-GALACTOSE

被引：27

作者：

HASELEY, SR

WILKINSON, SG

机构：

[1] School of Chemistry, University of Hull

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1995年 / 233卷 / 03期

关键词：

ACINETOBACTER BAUMANNII; LIPOPOLYSACCHARIDE; O-ANTIGEN;

D O I：

10.1111/j.1432-1033.1995.899_3.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A polysaccharide containing D-galactose, 2-deoxy-2-N-acetylamino-D-galactose and 3,6-dideoxy-3-N(D-3-hydroxybutyryl)amino-D-galactose, probably corresponding to the lipopolysaccharide side chain, was obtained from an aqueous phenol extract of isolated cell walls from Acinetobacter baumannii strain O2. By means of NMR studies and chemical degradations, the repeating unit of the polymer was identified as a branched hexasaccharide of the structure shown, where Fuc3N represents 3-amino-3,6-dideoxygalactose and R represents D-3-hydroxybutyryl. Serological tests indicated that the polymer corresponded to the O2 antigen.

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页码：899 / 906

页数：8

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