INDUCTIVE INFLUENCES OF DEMINERALIZED DENTIN AND BONE-MATRIX ON PULP CELLS - AN APPROACH OF SECONDARY DENTINOGENESIS

被引:48
作者
TZIAFAS, D
KOLOKURIS, I
机构
[1] Department of Dental Pathology and Therapeutics, School of Dentistry, Aristotle University of Thessaloniki
关键词
D O I
10.1177/00220345900690011301
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
The effects of demineralized dentin and bone matrix on dental ectomesenchymal cells were evaluated after observation periods of twa or three weeks. Autogenous dentin and bone matrix, obtained from the crowns of primary molars or maxillary cortical bone, respectively, were demineralized with 3% acetic acid and implanted into pulpal or papilla sites of erupting dog teeth: first molars, fourth premolars, and canines. Dentin histogenesis associated with odontoblastic arrangement was demonstrated in relation to all dentin implants in pulpal sites. Deposition of osteodentin, followed in some areas by tubular predentin formation, was observed in contact with bone implants in pulpal sites. In papilla sites, the dentin implantation exhibited bone-like matrix formation, while bone implants were encapsulated by connective tissue. The interactions of pulp cells with demineralized dentin matrix constitute a model for experimental inductian of secondary dentinogenesis and odontoblast-like cell differentiation. © 1990, SAGE Publications. All rights reserved.
引用
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页码:75 / 81
页数:7
相关论文
共 43 条
[11]   CELLULAR MECHANICS OF DENTINAL BRIDGE REPAIR USING THYMIDINE-H-3 [J].
FITZGERALD, M .
JOURNAL OF DENTAL RESEARCH, 1979, 58 :2198-2206
[12]  
INOUE T, 1981, Bulletin of Tokyo Dental College, V22, P213
[13]   INDUCTION OF CHONDROGENESIS IN MUSCLE, SKIN, BONE-MARROW, AND PERIODONTAL-LIGAMENT BY DEMINERALIZED DENTIN AND BONE-MATRIX INVIVO AND INVITRO [J].
INOUE, T ;
DEPORTER, DA ;
MELCHER, AH .
JOURNAL OF DENTAL RESEARCH, 1986, 65 (01) :12-22
[14]   ACELLULAR DENTAL MATRICES PROMOTE FUNCTIONAL-DIFFERENTIATION OF AMELOBLASTS [J].
KARCHERDJURICIC, V ;
STAUBLI, A ;
MEYER, JM ;
RUCH, JV .
DIFFERENTIATION, 1985, 29 (02) :169-175
[15]  
Kollar EJ, 1983, EPITHELIAL MESENCHYM, P27
[16]  
LESOT H, 1979, BIOL CELLULAIRE, V34, P23
[17]  
LESOT H, 1986, J EMBRYOL EXP MORPH, V96, P195
[18]   IMMUNOFLUORESCENT LOCALIZATION OF COLLAGENS, FIBRONECTIN, AND LAMININ DURING TERMINAL DIFFERENTIATION OF ODONTOBLASTS [J].
LESOT, H ;
OSMAN, M ;
RUCH, JV .
DEVELOPMENTAL BIOLOGY, 1981, 82 (02) :371-381
[19]   DECALCIFIED, LYOPHILIZED BONE ALLOGRAFTS FOR USE IN HUMAN PERIODONTAL DEFECTS [J].
LIBIN, BM ;
WARD, HL ;
FISHMAN, L .
JOURNAL OF PERIODONTOLOGY, 1975, 46 (01) :51-56
[20]   THE EXTRACELLULAR-MATRIX OF THE DENTAL-PULP AND DENTIN [J].
LINDE, A .
JOURNAL OF DENTAL RESEARCH, 1985, 64 :523-529