BORANES IN SYNTHESIS .1. ASYMMETRIC-SYNTHESIS OF BETA-AMINO ALCOHOLS - A FACILE CONVERSION OF ENAMINES TO THE CORRESPONDING BETA-AMINO ALCOHOLS IN HIGH ENANTIOMERIC PURITY

被引：20

作者：

FISHER, GB

GORALSKI, CT

NICHOLSON, LW

SINGARAM, B

机构：

[1] UNIV CALIF SANTA CRUZ,DEPT CHEM & BIOCHEM,SANTA CRUZ,CA 95064

[2] DOW CHEM CO USA,PHARMACEUT PROC RES & ANALYT SCI,MIDLAND,MI 48674

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(00)61541-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric hydroboration of aldehyde enamines with (d)Ipc2BH at 0-degrees-C, followed by oxidation with NaOH(s)/H2O2, yields the corresponding beta-amino alcohols in good yields and high enantiomeric excess.

引用

页码：7693 / 7696

页数：4

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