6-ALPHA-HYDROXYEURYCOMALACTONE, A QUASSINOID FROM EURYCOMA-LONGIFOLIA

被引：24

作者：

CHAN, KL

IITAKA, Y

NOGUCHI, H

SUGIYAMA, H

SAITO, I

SANKAWA, U

机构：

[1] UNIV TOKYO, FAC PHARMACEUT SCI, TOKYO 113, JAPAN

[2] KYOTO UNIV, FAC ENGN, DEPT SYNTHET CHEM, KYOTO 606, JAPAN

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 12期

关键词：

EURYCOMA-LONGIFOLIA; SIMAROUBACEAE; ROOTS; 6-ALPHA-HYDROXYEURYCOMALACTONE; EURYCOMALACTONE; QUASSINOIDS; STRUCTURAL ELUCIDATION; NON-DNA CLEAVAGE;

D O I：

10.1016/0031-9422(92)80461-M

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of 6alpha-hydroxyeurycomalactone, a new C19 quassinoid, isolated from the roots of Eurycoma longifolia has been established from spectral and by single crystal X-ray analysis; eurycomalactone was also isolated. The cytotoxic activity of some quassinoids from this plant is not mediated through DNA cleaving properties.

引用

页码：4295 / 4298

页数：4

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