DIRECT ENANTIOSELECTIVE SYNTHESIS OF SYN-1,3-DIOLS BY THE REACTION OF ALDEHYDES WITH ENOL SILYL ETHERS IN THE PRESENCE OF A CHIRAL BORANE COMPLEX - SUCCESSIVE ASYMMETRIC ALDOL REACTION AND ASYMMETRIC REDUCTION WITH ONE PROMOTER

被引：27

作者：

KANEKO, Y ^{[1
]}

MATSUO, T ^{[1
]}

KIYOOKA, S ^{[1
]}

机构：

[1] KOCHI UNIV,DEPT CHEM,KOCHI 780,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 24期

关键词：

ENANTIOSELECTIVITY; SYN-1,3-DIOL; ASYMMETRIC ALDOL REACTION; CHIRAL BORANE;

D O I：

10.1016/S0040-4039(00)73125-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A stoichiometric amount of the chiral borane 1 turned out to successively promote the asymmetric aldol reaction of aldehydes with enol silyl ethers and the following asymmetric reduction in one pot to afford syn-1,3-diols with high enantioselectivity.

引用

页码：4107 / 4110

页数：4

共 11 条

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