STRUCTURE OF 1,2,4-TRIDEOXY-1,4-IMINO-3,5 6,7-DI-O-ISOPROPYLIDENE-L-GLYCERO-D-GLUCO-OCTITOL - A KEY INTERMEDIATE IN THE ENANTIOSELECTIVE SYNTHESIS OF 8-EPICASTANOSPERMINE

被引：1

作者：

GALLAGHER, T ^{[1
]}

GILES, ME ^{[1
]}

MAHON, MF ^{[1
]}

MOLLOY, KC ^{[1
]}

HADLEY, MS ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,HARLOW CM19 5AD,ENGLAND

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1993年 / 49卷

关键词：

D O I：

10.1107/S0108270192004517

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5-(2,2-Dimethyl-4a,6,7,7a-tetrahydro-2H,-4H-[1,3]dioxino[5,4-b]pyrrol-4-yl)-2,2-dimethyl-4,5-dihydro-2H-1,3-dioxole-4-methanol, C14H25NO5, M(r) =287.4, trigonal, P3(2)21, a = 11.831 (2), c = 19.948 (7) angstrom, V = 2418.1 angstrom3, Z = 6, D(x) = 1.18 g cm-3, A(Mo Ka) = 0. 71069 angstrom, mu = 0.54 cm-1, F(000) = 936, room temperature, R = 0.0707, wR = 0.0780 for 1628 unique reflections. The structure of the title compound shows it to contain S, R, S stereochemistry at C1, C8a and C8 (castanospermine numbering), respectively. Molecules dimerize in a head-to-tail manner in the solid state through O-H...N hydrogen bonds.

引用

页码：40 / 42

页数：3