DETECTION OF OLIGONUCLEOTIDE DUPLEX FORMS BY ION-SPRAY MASS-SPECTROMETRY

被引：126

作者：

GANEM, B ^{[1
]}

LI, YT ^{[1
]}

HENION, JD ^{[1
]}

机构：

[1] CORNELL UNIV,NEW YORK STATE COLL VET MED,ITHACA,NY 14850

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)60314-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three representative examples of duplex DNA, each eight base pairs in length, have been examined by ion-spray mass spectrometry. The ability to detect base-paired duplex ions in each case further indicates the use of this technique for monitoring noncovalent interactions in biological systems.

引用

页码：1445 / 1448

页数：4

共 11 条

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