COMPUTATIONAL FLOW OPTIMIZATION OF ROTARY BLOOD PUMP COMPONENTS

被引:42
作者
ANTAKI, JF [1 ]
GHATTAS, O [1 ]
BURGREEN, GW [1 ]
HE, BC [1 ]
机构
[1] CARNEGIE MELLON UNIV, DEPT CIVIL ENGN, COMPUTAT MECH LAB, PITTSBURGH, PA 15213 USA
关键词
COMPUTATIONAL FLUID DYNAMICS; DESIGN OPTIMIZATION; SHAPE OPTIMIZATION; BLOOD TRAUMA; ARTIFICIAL ORGANS; MATHEMATICAL MODELS;
D O I
10.1111/j.1525-1594.1995.tb02389.x
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In an effort to improve and automate the fluid dynamic design of rotary blood pumps, a coupled com putational fluid dynamics (CFD) shape optimization methodology has been developed and implemented. This program couples a finite element flow simulation with a gradient-based optimization routine to modify automatically the shape of an initial candidate blood path, according to a variety of desired fluid dynamic criteria, including shear stress, vorticity/circulation, and viscous dissipation. Preliminary results have led to both intuitive and nonintuitive transformations of the initial blood flow paths for both internal and external flows. This application of computer design optimization offers the ability to explore a much broader design space much more efficiently than would be possible with traditional parametric methods. It is believed that this computer tool can assist developers of rotary blood pumps in designing blood-wetted components that minimize thrombosis and hemolysis while simultaneously providing maximum flow performance.
引用
收藏
页码:608 / 615
页数:8
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