SELECTIVE DETERMINATION OF PEPTIDES CONTAINING SPECIFIC AMINO-ACID-RESIDUES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND CAPILLARY ELECTROPHORESIS

被引：20

作者：

CUI, H ^{[1
]}

LEON, J ^{[1
]}

REUSSAET, E ^{[1
]}

BULT, A ^{[1
]}

机构：

[1] UNIV UTRECHT,FAC PHARM,DEPT PHARMACEUT ANAL,3584 CA UTRECHT,NETHERLANDS

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 704卷 / 01期

关键词：

D O I：

10.1016/0021-9673(95)00167-L

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

HPLC and CE methods for the selective determination of peptides containing cysteine, arginine, tryptophan, tyrosine and proline are reviewed. Chemical derivatization combined with UV-visible and fluorescent detection is the most often used method. The derivatization conditions, sensitivities, advantages, disadvantages and applications of these methods are discussed. Related methods are also considered.

引用

页码：27 / 36

页数：10

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