IMMUNOLOGICAL RESPONSES IN PATIENTS WITH LEPROMATOUS LEPROSY

被引：45

作者：

REA, TH

QUISMORIO, FP

HARDING, B

NIES, KM

DISAIA, PJ

LEVAN, NE

FRIOU, GJ

机构：

[1] UNIV SO CALIF, SCH MED, DEPT INTERN MED, DERMATOL SECT, LOS ANGELES, CA 90033 USA

[2] UNIV SO CALIF, SCH MED, DEPT OBSTET & GYNECOL, GYNECOL ONCOL SECT, LOS ANGELES, CA 90033 USA

[3] UNIV SO CALIF LOS ANGELES CTY MED CTR, DEPT DERMATOL, LOS ANGELES, CA 90033 USA

[4] UNIV SO CALIF LOS ANGELES CTY MED CTR, DEPT INTERN MED, LOS ANGELES, CA 90033 USA

[5] UNIV SO CALIF LOS ANGELES CTY MED CTR, DEPT OBSTET & GYNECOL, LOS ANGELES, CA 90033 USA

[6] UNIV SO CALIF, SCH MED, DEPT INTERN MED, CLIN IMMUNOL & RHEUMAT DIS SECT, LOS ANGELES, CA 90033 USA

来源：

ARCHIVES OF DERMATOLOGY | 1976年 / 112卷 / 06期

关键词：

D O I：

10.1001/archderm.112.6.791

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Immunologic responses were measured in 46 patients with lepromatous leprosy. These patients were not distinguishable from controls on the basis of responses to soluble intradermal antigens [purified protein derivative, streptokinase-streptodornase, histoplasmin, Trichophyton and Candida albicans antigens], sensitization to contactants, peripheral blood T[thymus-derived]- and B[bone marrow-derived]-cell percentages, in vitro lymphocyte responses to a mitogen [phytohemagglutinin], or the prevalence of autoantibodies. Generalized immunologic abnormalities in patients with lepromatous leprosy are neither predisposing causes nor necessary accompaniments of lepromatous leprosy, but are probably remote sequelae of the illness. The generalized immunologic abnormalities reported in other diseases are likely to be remote sequelae of the particular illness.

引用

页码：791 / 800

页数：10

共 63 条

[11] RELATIONSHIP OF LATEX FIXATION TEST TO CLINICAL AND SEROLOGIC MANIFESTATIONS OF LEPROSY [J].