NEUROPSYCHOLOGICAL DEFICITS AND SLEEP IN MYOTONIC-DYSTROPHY

被引：32

作者：

BROUGHTON, R ^{[1
]}

STUSS, D ^{[1
]}

KATES, M ^{[1
]}

ROBERTS, J ^{[1
]}

DUNHAM, W ^{[1
]}

机构：

[1] UNIV OTTAWA,OTTAWA K1N 6N5,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 1990年 / 17卷 / 04期

关键词：

D O I：

10.1017/S0317167100030985

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Eight patients with myotonic dystrophy underwent comprehensive neuropsychological testing and overnight polysomnography to assess whether the waking cognitive impairment might be attributable to sleep structure abnormalities or to sleep-related respiratory problems. Patients showed substantial neuropsychological deficits, fragmented nocturnal sleep and, in half the patients, sleep apnea and/or hypopnea both mainly of central type. There was no statistically significant correlation between the degree of daytime cognitive deficit and the degree of sleep fragmentation or of respiratory problems at night. It was concluded that the neuropsychological deficit in mytonic dystrophy cannot be attributed to a secondary effect of nocturnal sleep apnea or sleep disruption but probably represents a direct effect of CNS lesions. © 1990, Canadian Neurological Sciences Federation. All rights reserved.

引用

页码：410 / 415

页数：6

共 28 条

[11] DRIVING SIMULATOR PERFORMANCE IN PATIENTS WITH SLEEP-APNEA
FINDLEY, LJ
FABRIZIO, MJ
KNIGHT, H
NORCROSS, BB
LAFORTE, AJ
SURATT, PM
[J]. AMERICAN REVIEW OF RESPIRATORY DISEASE, 1989, 140 (02): : 529 - 530
[12] GLASS GV, 1970, STATISTICAL METHODS
[13] GOLDENBERG F, 1977, SLEEP, P439
[14] NEUROPSYCHOLOGICAL DYSFUNCTION IN SLEEP-APNEA
GREENBERG, GD
WATSON, RK
DEPTULA, D
[J]. SLEEP, 1987, 10 (03) : 254 - 262
[15] GUILLEMINAULT C, 1978, SLEEP, V61, P19
[16] GUILLEMINAULT C, 1982, SLEEPING WAKING DISO
[17] SEVERE OBSTRUCTIVE SLEEP-APNEA .2. ASSOCIATED PSYCHOPATHOLOGY AND PSYCHOSOCIAL CONSEQUENCES
KALES, A
CALDWELL, AB
CADIEUX, RJ
VELABUENO, A
RUCH, LG
MAYES, SD
[J]. JOURNAL OF CHRONIC DISEASES, 1985, 38 (05): : 427 - 434
[18] LEYGONIEGOLDENBERG F, 1977, REV NEUROL-FRANCE, V133, P255
[19] FATAL FAMILIAL INSOMNIA AND DYSAUTONOMIA WITH SELECTIVE DEGENERATION OF THALAMIC NUCLEI
LUGARESI, E
MEDORI, R
MONTAGNA, P
BARUZZI, A
CORTELLI, P
LUGARESI, A
TINUPER, P
ZUCCONI, M
GAMBETTI, P
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1986, 315 (16) : 997 - 1003
[20] Rechtschaffen A, 1968, NIH PUBLICATION, V204

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